Kikuchi disease – a rare cause of pyrexia of unknown origin

Pyrexia of unknown origin: Kikuchi-Fujimoto disease.

A case of Kikuchi-Fujimoto disease is presented in the context of pyrexia of unknown origin. Although no specific etiology has been identified, several reported cases are associated with a variety of viruses, toxoplasma, or systemic lupus erythematosus. We present a case and discuss the implications for management.

Pyrexia of unknown origin.

Pyrexia of Unknown Origin

One of the most challenging problem a physician used to face in day to day practice is the evaluation of patients with prolonged pyrexia—a truly significant test of his clinical skills. Causes of PUO vary according to geographical area, health care setup, investigations facilities, and physicians’ attitude. Because of socioeconomic and other factors, infectious diseases are still very common in...

Kikuchi's Disease: A Rare Cause of Fever of Unknown Origin.

Kikuchi Fujimoto Disease (KFD) or histiocytic necrotizing lymphadenitis can present with unexplained fever and lymphadenopathy. It is often mistaken for more serious conditions like malignant lymphoma or tuberculosis. First case was described by Kikuchi in Japan, very few cases have been reported in Pakistan. A middle aged female presented with fever and body aches for one month. She was invest...

An uncommon endocrine cause of pyrexia of unknown origin.

We report a previously healthy 43 yr old male who presented with prolonged fever, weight loss and neck pain for 3 weeks. Even after extensive work up for the possible causes of pyrexia, the cause remained elusive. In view of persistent tachycardia and neck pain, possibility of subacute thyroiditis was suspected. Thyroid function test (TFT) revealed thyrotoxicosis, which on further evaluation wa...